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Citizen Science Projects Surging, But Often Lack IRB Ethical Oversight
Failure to return results, exploitation of participants, poor quality data, and power imbalance are top ethical worries. Citizen scientists should pay attention to issues of power and exploitation, and think about what processes to use to stay ahead of those concerns.
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Diagnosing and Managing Pediatric Foreign Body Ingestions: Part II
The process of diagnosing and managing foreign bodies has changed over the last few years. In Part II, the authors discuss not only the process for managing the majority of foreign bodies, but also unique ingestions that require special care.
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Glycemic Control During Labor in Women with Diabetes
This study demonstrated an increased risk of neonatal hypoglycemia in neonates born to patients with diabetes as the result of maternal hyperglycemia in labor. However, strict intrapartum maternal glycemic control appeared to be associated with a reduced risk of neonatal hypoglycemia only in patients with gestational diabetes on medication, but not for other diabetes subtypes.
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Oral vs. IV Iron for the Treatment of Iron-Deficiency Anemia in Pregnant Women
Compared to oral iron, intravenous iron reduced maternal anemia at delivery (40% vs. 85%, P = 0.039), and rates of maternal hemoglobin < 10 g/dL were lower with intravenous iron compared to oral iron (10% vs. 54%, P = 0.029). Rates of mild to moderate adverse events were similar between the two groups, and no severe adverse reactions were noted with intravenous iron.
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The Pseudogestational Sac of Ectopic Pregnancy: Does it Really Matter?
In this retrospective cohort study of 1,236 women, the rate (2.2%) of ectopic pregnancy was rare among women with a fluid collection (or pseudosac) in the uterus. The size of the fluid collection was not predictive of ectopic pregnancy. The presence of an intrauterine fluid collection decreased the risk of ectopic pregnancy (adjusted relative risk, 0.09; 95% confidence interval, 0.05-0.19) after adjusting for age and the presence of bleeding.
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Is the Timing of Interval Postpartum Insertion of Intrauterine Device Associated with the Frequency of Complications?
Having an intrauterine device (IUD) inserted at four to eight weeks postpartum was associated with higher frequency of uterine perforation, but not higher frequency of expulsion, compared to IUD insertion at nine to 36 weeks postpartum. Overall, perforation and expulsion rates were low.
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Clindamycin Vaginal Gel 2% (Xaciato)
Clindamycin gel can be prescribed to treat bacterial vaginosis in women age 12 years and older.
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Screen Older Heart Failure Patients for Transthyretin Cardiac Amyloidosis
A screening study of heart failure patients ≥ age 60 years, left ventricular ejection fraction ≥ 40%, and left ventricle wall thickness ≥ 12 mm revealed 6.3% prevalence of transthyretin cardiac amyloidosis, a highly treatable disease.
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Is Physical Activity Associated with Mortality Risk in Parkinson’s Disease?
In individuals with Parkinson’s disease (PD), physical activity (PA) at all intensities was associated with lower all-cause mortality rates, with the greatest reduction seen in individuals who maintained PA before and after PD diagnosis.
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Multiple Sclerosis and Immune Response to COVID-19 Vaccination
A large group of patients with multiple sclerosis taking various disease-modifying therapies did not respond uniformly to COVID-19 vaccination.